ADMIN: OPINION. Marijuana is still classified by those who control the Drug Enforcement Agency (DEA) as an illegal Schedule I drug which has no accepted medical use and laden with significant “side effects” like euphoria and psychosis. Nothing could be further from the scientific truth. The weight of the scientific evidence that marijuana is highly therapeutic is so overwhelming from what the entire Federal Government agents purport to clam that the People should better understand that their political system has been bought by pharmaceutical drugs cartels and other corrupt organizations. (1).
Moreover, the facts show that those who villify this plant are the same individuals who demonize people like Dr Oz for promoting holistic medicine and criticiaing GMO foods, all of which mirrors deep corruption of the present political-economic-medical system. (2).
Practically all non biased studies (Pubmed registers has registered thousands of these studies) have shown that medical marijuana is safe and effective in controlling chronic pain, alleviating nausea and vomiting associated with chemotherapy, treating the AIDS’ wasting syndrome, helping with the immune system and excessive inflammation, stress, anxiety, sleep, appetite and controlling muscle spasms due to multiple sclerosis with few if any side effects while promoting wellbeing. (3) Just for chronic pain control, PubMed shows that there have been 951 studies on marijuana and pain control, all of which show that marijuana helps to better control pain. (4)
Furthermore, recent scientific studies from the vast international scientific community, hundreds of them, all published in peer reviewed journals, (see a few below) have shown that epilepsy, mental diseases, including Alzheimers and, among other pathologies, most cancers significantly benefited from this venerable plant. These studies state that the alleviating benefits of marijuana outweigh the negative effects of the drug, and recommend that marijuana be administered to patients who have failed to respond to other therapies.
Despite supporting robust evidence, the DEA, Congress and the Justice Department refuse to reclassify marijuana as a Schedule II drug, which would allow physicians to prescribe marijuana to suffering patients. And the FDA has limited its medicinal use to only a few conditions, despite hundreds of successful studies and preclinical trials, while 33 percent of the FDA’s approved drugs have had only one corroborating preclinical trial. (5)
The use of medical marijuana has continued to gain support among states, to this day 23 states have recognized the medical necessity to legalize cannabis, including DC and four of which for recreational purposes. This is in stark contrast to the federal government’s stance of zero-tolerance, which has led to a heated legal debate in the United States.
After reviewing the relevant scientific data and grounding the issue in ethical principles like beneficence and nonmaleficence, inter alia, we can assert that there there is a strong argument for allowing physicians to prescribe marijuana, notwithstanding the Federal Government’s harassment.
Patients have a basic right to all beneficial treatments and to deny them this right violates their basic human rights, the Constitution and dignity. Even though Republicans have distinguished themselves to be extremely against internationally recognized human rights law and the Constitution, the Democrats follow close behind. Most of the members of these two political parties have become hired guns for a significant section of American big business, i.e., those who have degraded to the subhuman level of corruption, hubris and ineptitude (see our older posts).
The legal consequence thereto should be the impeachment of the Judges who continue to harass citizens with an unconstitutional 1970 statute. (6).
But this social and legal necessity is quasi impossible without the restructuing of a new and more constitutional-friendly US Supreme court and without vacating (canceling) all of the US Congress, most (not all, just most) members of which refuse to abide by the Constitution on just about every significant front, from public health to the general welfare of the People, basic freedoms and social justice. (7)
Because those in charge of the three major Branches of the Government continue to monopolize the laws, the mainstream media, the electoral political system and the State’s coercitive powers, the People are unable to be sovereign and healthy and satisfy most of their basic needs.
It is therefore time for the People to rise up, to break their chains, to change lifestyles and attitudes, to embrace holistic health and to become masters of their own fate and find non violent, legal and human rights ways to oust the treasonous individuals who have gangrened public service, duped the People and tarnished the Constitution and who are massively present, like metastatic invasive cancer stem cells, in all of the Government’s major organs, from the Judicary (including the crippled US Supreme Court), to the Executive (including the oval Office) and the U.S. Legislature (most of which has been bought by corruption money) and most of whom claim to represent the entire Nation while all they mostly do is work for unconstitutional laws (like this 1070 anti marijuana law) and the corporate toxic industries cartel that is debilitating the Nation and destroying the country’s social fabric, its public finances, its public education, and, inter alia, its public health system. (8)
So yes, this is a respectful call for civil disobedience, in the best of Ghandi’s, Paine’s, Zola’s, Yashua’s and Martin Luther King’s tradition, against the public oppressors the People were manipulated to vote for. In this perspective, a human rights Cannabis Science and public policy Institute will be shortly established to help the human rights movement to be more robust in the field of medicine and public health. So it be ordered. Ch J.
(1). See the new documenatry movie called “Boughtmovie” for some of the evidence.
(2″ See : http://www.naturalnews.com/049395_Doctor_Oz_Monsanto_Mafia_glyphosate_toxicity.html and http://money.cnn.com/2015/04/19/media/dr-oz-response/
See also our facebook page for additional evidence. https://www.facebook.com/holisticmedicinelaw?ref=br_tf
(3). When this plant is judiciously used, like with wine and anything that has a big therapeutic bang. A pubmed search indicates over 21,000 studies on marijuana.
(4). And contrarily to morphine, marijuana does not suppress the immune or respiratory systems, let alone lead to severe constipation and a hastened death.
(5). Like with the GMO approval process which was based on a 9 months rat study, and the FDA continues to approve GMO foods to this day despite the growing evidence that GMO foods are harmful (Cf among other studies the French team study under Dr Serillini who proved that with the same rats, the same cancer and the same gmo diet, but fed GMO foods for two years, the rats developed different pathologies, including tumors). Just like with Sloan Katering Cancer center (with the laetrile fraud) and so many other examples, the U.S. Food and Drug Administration has distinguised itself, via its appointed commissioners, by massively poisoning the American population with not only many toxic insufficiently tested drugs, but also has numrously broken the law and repeatedly lied in order to usher genetically engineered foods onto the market without the safety testing that’s required by federal statute. As a result, for fifteen years America’s families have been regularly ingesting a group of novel products that the FDA’s own scientific staff had previously determined to be unduly hazardous to human health and regarding which a French scientists team has shown to lead cancer and other pathologies, including but not limited to leaky gut syndrome. See this recent http://www.amazon.com/Altered-Genes-Twisted-Truth-Systematically/dp/0985616903/ And see this link for the memorial sloan kettering cancer center fraud: https://secondopinionlaetrileatsloankettering.vhx.tv
(6). Just today, a young man in his twenties received a 55 years prison sentence under federal law for having sold close to one thousand dollars worth of cannabis in order to satisfy some of his basic needs the government was not able to offer him. See https://www.facebook.com/holisticmedicinelaw?ref=br_tf
(7). Recently, this week, the US Congress gave additional tax breaks to millionaires and billionaires while the low and mid-income Americans continue to get burried under stress, diseases, discrimination, oppression and misery. While the country’s soil, environment and food supplies continue to be depleted and poisoned to death . Cf. https://www.youtube.com/watch?v=aCUbvOwwfWM
(8). Again, not all of the major public decision making elite, but most. In all of the three Branches of the Government, there are responsible people who voice concern and try to serve the best interests of the People. But because the majority of those who control the three Branches of the Government have been bought by corrupt organizations, the entire political system should be overhauled.
BELOW, JUST A FEW (OUT OF OVER 500) PUBLISHED PEER REVIEWED STUDIES THAT PROVE BEYOND ANY REASONABLE DOUBT THAT CANNABIS MEDICINE IS A HEALTH NECESSITY THAT NEEDS MORE FEDERAL PROTECTION AND PROMOTION THAN THE ONGOING FEDERAL HARASSMENT
Mol Cancer Ther 2007;6(11):2921–7]
Cannabidiol as a novel inhibitor of Id-1 gene expression in aggressive breast cancer cells
Sean D. McAllister, Rigel T. Christian, Maxx P. Horowitz, Amaia Garcia and Pierre-Yves Desprez
Invasion and metastasis of aggressive breast cancer cells is the final and fatal step during cancer progression, and is the least understood genetically. Clinically, there are still limited therapeutic interventions for aggressive and metastatic breast cancers available. Clearly, effective and nontoxic therapies are urgently required. Id-1, an inhibitor of basic helix-loop-helix transcription factors, has recently been shown to be a key regulator of the metastatic potential of breast and additional cancers. Using a mouse model, we previously determined that metastatic breast cancer cells became significantly less invasive in vitro and less metastatic in vivo when Id-1 was down-regulated by stable transduction with antisense Id-1. It is not possible at this point, however, to use antisense technology to reduce Id-1 expression in patients with metastatic breast cancer. Here, we report that cannabidiol (CBD), a cannabinoid with a low-toxicity profile, could down-regulate Id-1 expression in aggressive human breast cancer cells. The CBD concentrations effective at inhibiting Id-1 expression correlated with those used to inhibit the proliferative and invasive phenotype of breast cancer cells. CBD was able to inhibit Id-1 expression at the mRNA and protein level in a concentration-dependent fashion. These effects seemed to occur as the result of an inhibition of the Id-1 gene at the promoter level. Importantly, CBD did not inhibit invasiveness in cells that ectopically expressed Id-1. In conclusion, CBD represents the first nontoxic exogenous agent that can significantly decrease Id-1 expression in metastatic breast cancer cells leading to the down-regulation of tumor aggressiveness.
Molecular Cancer 2010, 9:196 doi:10.1186/1476-4598-9-196
Cannabinoids reduce ErbB2-driven breast cancer progression through Akt inhibition
María M Caffarel16, Clara Andradas1, Emilia Mira2, Eduardo Pérez-Gómez1, Camilla Cerutti16, Gema Moreno-Bueno3, Juana M Flores4, Isabel García-Real4, José Palacios5, Santos Mañes2, Manuel Guzmán1 and Cristina Sánchez1*
ErbB2-positive breast cancer is characterized by highly aggressive phenotypes and reduced responsiveness to standard therapies. Although specific ErbB2-targeted therapies have been designed, only a small percentage of patients respond to these treatments and most of them eventually relapse. The existence of this population of particularly aggressive and non-responding or relapsing patients urges the search for novel therapies. The purpose of this study was to determine whether cannabinoids might constitute a new therapeutic tool for the treatment of ErbB2-positive breast tumors. We analyzed their antitumor potential in a well established and clinically relevant model of ErbB2-driven metastatic breast cancer: the MMTV-neu mouse. We also analyzed the expression of cannabinoid targets in a series of 87 human breast tumors.
Our results show that both Δ9-tetrahydrocannabinol, the most abundant and potent cannabinoid in marijuana, and JWH-133, a non-psychotropic CB2 receptor-selective agonist, reduce tumor growth, tumor number, and the amount/severity of lung metastases in MMTV-neu mice. Histological analyses of the tumors revealed that cannabinoids inhibit cancer cell proliferation, induce cancer cell apoptosis, and impair tumor angiogenesis. Cannabinoid antitumoral action relies, at least partially, on the inhibition of the pro-tumorigenic Akt pathway. We also found that 91% of ErbB2-positive tumors express the non-psychotropic cannabinoid receptor CB2.
Taken together, these results provide a strong preclinical evidence for the use of cannabinoid-based therapies for the management of ErbB2-positive breast cancer.
Bol Asoc Med P R. 2014;106(3):55-9.
Use and medicalization of marihuana in cancer patients.
Pedro E, Rodríguez FM.
Anecdotal reports and some clinical studies suggest that marihuana (Cannabis sativa) is effective in treating a variety of conditions such as glaucoma, migraine, pain, spasticity of multiple sclerosis, anorexia, insomnia, depression, nausea and vomiting. One of the diseases mostly associated to a beneficial effect from marihuana is cancer. Twenty-one states of the United States including the District of Columbia have approved the use of marihuana for cancer and other medical conditions. In Puerto Rico, public debate on criminal penalty removal and medicalization of marihuana has intensified. It is considered essential for health professionals to have strong scientific evidence on the effectiveness and safety of medications or substances when recommending them for treating illness. This article discusses scientific evidence and information provided by prestigious organizations on the effectiveness and safety of marihuana and its derivatives in cancer patients.
Clin Pharmacol Ther. 2015 Mar 16. doi: 10.1002/cpt.108. [Epub ahead of print]
Cannabis in cancer care.
Abrams DI1, Guzman M.
Cannabis has been used in medicine for thousands of years prior to achieving its current illicit substance status. Cannabinoids, the active components of Cannabis sativa, mimic the effects of the endogenous cannabinoids (endocannabinoids), activating specific cannabinoid receptors, particularly CB1 found predominantly in the central nervous system and CB2 found predominantly in cells involved with immune function. Delta-9-tetrahydrocannabinol, the main bioactive cannabinoid in the plant, has been available as a prescription medication approved for treatment of cancer chemotherapy-induced nausea and vomiting and anorexia associated with the AIDS wasting syndrome. Cannabinoids may be of benefit in the treatment of cancer-related pain, possibly synergistic with opioid analgesics. Cannabinoids have been shown to be of benefit in the treatment of HIV-related peripheral neuropathy, suggesting that they may be worthy of study in patients with other neuropathic symptoms. Cannabinoids have a favorable drug safety profile, but their medical use is predominantly limited by their psychoactive effects and their limited bioavailability.
Br J Pharmacol. 2013 Jan;168(1):76-8. doi: 10.1111/j.1476-5381.2012.02121.x.
Towards the use of non-psychoactive cannabinoids for prostate cancer.